Yellow Fever
Estimated Death Toll: > 50,000
Location: United States

During the 1793 yellow fever epidemic in Philadelphia, 5,000 or more people were listed in the official register of deaths between August 1 and November 9. The vast majority of them died of yellow fever, making the epidemic in the city of 50,000 people one of the most severe in United States history. By the end of September, 20,000 people had fled the city. The mortality rate peaked in October before frost finally killed the mosquitoes and brought an end to the epidemic in November. Doctors tried a variety of treatments but knew neither the origin of the fever nor that it was transmitted by mosquitoes. Wikipedia Reference »

Arch Street Ferry.jpg
By Engraving by William Birch, from The City of Philadelphia, 1800, Independence National Historical Park – Public Domain, Link

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