EPIDEMIC
Disease:
 Plague
Estimated Death Toll: > 20,100 in London
Location: London

In 1563 London experienced its worst episode of plague during the 16th Century. At least 20,136 people in London and surrounding parishes are recorded to have died of plague during this outbreak. Around 24% of London’s population ultimately perished, but the plague affected London’s unsanitary parishes and neighborhoods the most. Wikipedia Reference »

Civitas Londinium or The Agas Map of London.jpg
By Mike Calder, image of Civitas Londinium, Agas’ Map of London, c. 1570-1605 – Maps of Old London, London, Adam and Charles Black, 1908. Scanned & corrected Mike Calder., Public Domain, Link