History of Outbreaks

Timeline Story



DEATH TOLL

Pandemics (worldwide spread) and Epidemics (regional spread) with estimated numbers. See historical data below »

HIV AIDS

Cholera (Yearly)

Influenza (Yearly)

EBOLA

Pandemics and notable epidemics throughout history

429–426 BC

Plague of Athens

EPIDEMIC Disease: Unknown Estimated Death Toll: 75,000–100,000 Location: Greece The Plague of Athens was an epidemic that devastated the city-state of Athens in..Read More
165-180 AD

Antonine Plague

EPIDEMIC Disease: Unknown, Possibly Smallpox Estimated Death Toll: 5 – 10 Million Location: Roman Empire The Antonine Plague of 165 to 180..Read More
541-542 AD

Plague of Justinian

PANDEMIC Disease: Plague Estimated Death Toll: 25–50 million; 40% of population Location: Europe, Egypt, and West Asia The Plague of Justinian was a..Read More
1331–1353

Black Death

PANDEMIC Disease: Black Death Estimated Death Toll: 20–200 million; 20–60% of the European population Location: Europe, Asia, and North Africa The Black Death, also..Read More
1545–1548

Cocoliztli Epidemic of 1545–1548

EPIDEMIC Disease: Cocoliztli Epidemic of 1545–1548 Estimated Death Toll: 5–15 million (80% of population) Location: Mexico The cocoliztli epidemic or the great pestilence is a term given to..Read More
1563–1564

1563 London Plague

EPIDEMIC Disease: Plague Estimated Death Toll: > 20,100 in London Location: London In 1563 London experienced its worst episode of plague during the..Read More
1576–1580

Cocoliztli Epidemic of 1576

EPIDEMIC Disease: Cocoliztli Epidemic of 1576 Estimated Death Toll: 2–2.5 million (50% of the population) Location: Mexico The cocoliztli epidemic or the great pestilence is a term..Read More
1616–1619

1616 New England Epidemic

EPIDEMIC Disease: Unknown cause. The latest research suggests epidemic(s) of leptospirosis with Weil syndrome. Classic explanations include yellow fever, bubonic plague, influenza, smallpox, chickenpox, typhus, and syndemic infection of hepatitis B and hepatitis D. Estimated..Read More
1629–1631

Italian Plague of 1629–1631

EPIDEMIC Disease: Plague Estimated Death Toll: 280,000 Location: Italy The Italian Plague of 1629–1631 was a series of outbreaks of bubonic plague which ravaged..Read More
1665–1666

Great Plague of London

EPIDEMIC Disease: Plague Estimated Death Toll: 100,000 Location: England The Great Plague, lasting from 1665 to 1666, was the last major epidemic of..Read More
1668

Plague of France 1668

EPIDEMIC Disease: Plague Estimated Death Toll: 40,000 Location: France Facebook Twitter reddit LinkedIn Digg Delicious
1679

Great Plague of Vienna

EPIDEMIC Disease: Plague Estimated Death Toll: 76,000 Location: Austria The Great Plague of Vienna occurred in 1679 in Vienna, Austria, the imperial residence of the..Read More
1707–1709

Great Smallpox Epidemic

EPIDEMIC Disease: Smallpox Estimated Death Toll: 18,000 (36% of the population) Location: Iceland Facebook Twitter reddit LinkedIn Digg Delicious
1720-1722

Great Plague of Marseille

EPIDEMIC Disease: Plague Estimated Death Toll: 100,000 Location: France The Great Plague of Marseille was the last of the significant European outbreaks of bubonic..Read More
1738-1740

Great Plague of 1738

PANDEMIC Disease: Plague Estimated Death Toll: > 50,000 Location: Balkans The Great Plague of 1738 was an outbreak of the bubonic plague between 1738–1740..Read More
1770-1772

Russian Plague of 1770–1772

EPIDEMIC Disease: Plague Estimated Death Toll: > 50,000 Location: Russia The Russian plague epidemic of 1770–1772, also known as the Plague of 1771, was..Read More
1772

1772 Persia Plague

EPIDEMIC Disease: Plague Estimated Death Toll: > 2,000,000 Location: Persia Facebook Twitter reddit LinkedIn Digg Delicious
1793–1798

Yellow Fever Epidemic of 1793

EPIDEMIC Disease: Yellow Fever Estimated Death Toll: > 50,000 Location: United States During the 1793 yellow fever epidemic in Philadelphia, 5,000 or more people were listed..Read More
1817–1824

First Cholera Pandemic

PANDEMIC Disease: Cholera Estimated Death Toll: > 100,000 Location: Asia, Europe The first cholera pandemic (1817–24), also known as the first Asiatic cholera pandemic or Asiatic cholera,..Read More
1826–1837

Second Cholera Pandemic

PANDEMIC Disease: Cholera Estimated Death Toll: > 100,000 Location: Asia, Europe, North America The second cholera pandemic (1826–1837), also known as the Asiatic cholera pandemic, was a..Read More
1847–1848

Typhus Epidemic of 1847

EPIDEMIC Disease: Typhus Estimated Death Toll: > 20,000 Location: Canada The typhus epidemic of 1847 was an outbreak of epidemic typhus caused by..Read More
1846–1860

Third Cholera Pandemic

PANDEMIC Disease: Cholera Estimated Death Toll: > 1,000,000 Location: Asia, Europe, Africa, North America The third cholera pandemic (1846–60) was the third major outbreak of..Read More
1855–1960

Third Plague Pandemic

PANDEMIC Disease: Bubonic Plague Estimated Death Toll: > 12,000,000 Location: Worldwide The third plague pandemic was a major bubonic plague pandemic that began in Yunnan, China..Read More
1863–1875

Fourth Cholera Pandemic

PANDEMIC Disease: Cholera Estimated Death Toll: > 600,000 Location: Middle East The fourth cholera pandemic of the 19th century began in the Ganges Delta..Read More
1875

1875 Fiji Measles Outbreak

EPIDEMIC Disease: Measles Estimated Death Toll: 40,000 Location: Fiji Facebook Twitter reddit LinkedIn Digg Delicious
1899–1923

Sixth Cholera Pandemic

PANDEMIC Disease: Cholera Estimated Death Toll: > 800,000 Location: Middle East, North Africa, Eastern Europe, and Russia The sixth cholera pandemic (1899–1923) was a..Read More
1915–1926

1915 Encephalitis Lethargica Pandemic

PANDEMIC Disease: Encephalitis Lethargica Estimated Death Toll: 1,500,000 Location: Worldwide Facebook Twitter reddit LinkedIn Digg Delicious
1918–1920

Spanish Flu

PANDEMIC Disease: Influenza Estimated Death Toll: up to 100,000,000 Location: Worldwide The 1918 influenza pandemic was an unusually deadly influenza pandemic, the first of the..Read More
1957–1958

Asian Flu

PANDEMIC Disease: Influenza Estimated Death Toll: 2,000,000 Location: Worldwide Influenza A virus subtype H2N2 (A/H2N2) is a subtype of Influenza A virus. H2N2 has..Read More
1968–1969

Hong Kong Flu

PANDEMIC Disease: Influenza Estimated Death Toll: 1,000,000 Location: Worldwide The 1968 flu pandemic was a category 2 flu pandemic whose outbreak in 1968 and 1969..Read More
1960–Present

HIV/AIDS Pandemic

PANDEMIC Disease: HIV/AIDS Estimated Death Toll: > 32,000,000 Location: Worldwide HIV/AIDS is a global pandemic. As of 2018, approximately 37.9 million people are infected..Read More
2002-2004

SARS Outbreak

EPIDEMIC Disease: SARS (SARS-CoV-1) Estimated Death Toll: > 810 Location: Worldwide (29 territories) The 2002–2004 SARS outbreak was an epidemic involving severe acute respiratory..Read More
2008–2009

2008–2009 Zimbabwean Cholera Outbreak

EPIDEMIC Disease: Cholera Estimated Death Toll: 4,293 Location: Zimbabwe The 2008 Zimbabwean cholera outbreak was an epidemic of cholera affecting much of Zimbabwe from August..Read More
2009

2009 Flu Pandemic

PANDEMIC Disease: Influenza Estimated Death Toll: 203,000 Location: Worldwide The 2009 flu pandemic or swine flu was an influenza pandemic that lasted from early 2009 to late 2010, and..Read More
2010–Present

Haiti Cholera Outbreak

EPIDEMIC Disease: Cholera Estimated Death Toll: 9,985 (May 2017) Location: Hispaniola The 2010 Haitian cholera outbreak was the first modern large-scale outbreak of cholera – a..Read More
2012–Present

2012 Middle East Respiratory Syndrome Coronavirus

PANDEMIC Disease: Middle East Respiratory Syndrome (MERS) Estimated Death Toll: > 862 (as of 13 January 2020) Location: Worldwide Since 2012, an outbreak of Middle..Read More
2013–2016

Ebola Virus Epidemic in West Africa

PANDEMIC Disease: Ebola Virus Disease Estimated Death Toll: > 11,300 Location: Worldwide, mainly intense in West Africa The Western African Ebola virus epidemic..Read More
2015-2016

2015–16 Zika Virus Epidemic

EPIDEMIC Disease: Zika Virus Epidemic Estimated Death Toll: 53 Location: Worldwide In early 2015, a widespread epidemic of Zika fever, caused by the Zika..Read More
2019-2020

2019–20 Coronavirus Outbreak

PANDEMIC Disease: COVID-19 Estimated Death Toll: > 652,039 – As of 27 Jul 2020 Location: Worldwide The 2019–20 coronavirus outbreak is an ongoing public health..Read More



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